Sam Neill as Molloy. (Photo: Archive)
Mel Brooks. (Photo: Archive)
Cloris Leachman as Mrs. Glick. (Photo: Archive)
David Hyde Pierce as Cecil Terwiliger. (Photo: Archive)
Betty White. (Photo: Archive)
Joe Namath. (Photo: Archive)
Kirk Douglas as Chester J. Lampwick. (Photo: Archive)
Dennis Franz as “Homer.” (Photo: Archive)
Jeff Goldblum as MacArthur Parker. (Photo: Archive)
Willie Nelson. (Photo: Archive)
John Waters as John. (Photo: Archive)
Lawrence Tierney as Don Brodka. (Photo: Archive)
Spinal Tap. (Photo: Archive)
Bob Hope. (Photo: Archive)
John Goodman as Meathook. (Photo: Archive)
Eric Idle as Declan Desmond. (Photo: Archive)
Neil Patrick Harris as “Bart.” (Photo: Archive)
George Carlin and Martin Mull as Seth and Munchie. (Photo: Archive)
Jim Varney as Cooder. (Photo: Archive)
Daniel Clowes, Art Spiegelman and Alan Moore. (Photo: Archive)
Mark Hamill. (Photo: Archive)
Robert Goulet. (Photo: Archive)
Penny Marshall as Ms. Botz. (Photo: Archive)
Paul and Linda McCartney. (Photo: Archive)
Ringo Starr. (Photo: Archive)
Steve Allen. (Photo: Archive)
Lisa Kudrow as Alex. (Photo: Archive)
Pamela Reed as Ruth Powers. (Photo: Archive)
Donald Sutherland as Hollis Hurlbut. (Photo: Archive)
David Duchovny and Gillian Anderson as Mulder and Scully. (Photo: Archive)
Sab Shimono as Mr. Sparkle. (Photo: Archive)
Willem Dafoe as The Commandant. (Photo: Archive)
R. Lee Ermey as Col. Hapablap. (Photo: Archive)
Stephen Colbert as Colby. (Photo: Archive)
Linda Ronstadt. (Photo: Archive)
Over the years many celebrities have made cameo appearances on the long-running animated sitcom The Simpsons. We highlight some of the best ones!
