Adam West. (Photo: Archive)
Jay Mohr as Christopher Walken. (Photo: Archive)
Sara Gilbert as Laura. (Photo: Archive)
Dave Thomas as Rex Banner. (Photo: Archive)
Hank Williams Jr. (Photo: Archive)
Beverly D’Angelo as Lurleen Lumpkin. (Photo: Archive)
Tito Puente. (Photo: Archive)
Mandy Patinkin as Hugh. (Photo: Archive)
Conan O’Brien. (Photo: Archive)
George Harrison. (Photo: Archive)
Glenn Close as Mona Simpson. (Photo: Archive)
Kathleen Turner as Stacy Lovell. (Photo: Archive)
James Earl Jones as the Narrator. (Photo: Archive)
Michelle Pfieffer as Mindy. (Photo: Archive)
Patrick Stewart as Number One. (Photo: Archive)
Barry White. (Photo: Archive)
Rodney Dangerfield as Larry Burns. (Photo: Archive)
Stephen Hawking. (Photo: Archive)
The Cast of Cheers. (Photo: Archive)
Mickey Rooney. (Photo: Archive)
Leonard Nimoy. (Photo: Archive)
Dustin Hoffman as Mr. Bergstrom. (Photo: Archive)
Harvey Fierstein as Karl. (Photo: Archive)
Jon Lovitz as Artie Ziff. (Photo: Archive)
Meryl Streep as Jessica Lovejoy. (Photo: Archive)
Jack Lemmon as Frank Ormand. (Photo: Archive)
Michael Jackson as Leon Kompowski. (Photo: Archive)
Kelsey Grammer as Sideshow Bob. (Photo: Archive)
Albert Brooks as Hank Scorpio. (Photo: Archive)
Buzz Aldrin. (Photo: Archive)
Ron Taylor as Bleeding Gums Murphy. (Photo: Archive)
Ernest Borgnine. (Photo: Archive)
Johnny Cash as Homer’s Spirit Coyote. (Photo: Archive)
James Woods. (Photo: Archive)
The Springfield Isotopes. (Photo: Archive)
Over the years many celebrities have made cameo appearances on the long-running animated sitcom The Simpsons. We highlight some of the best ones!